Clinical Prediction Rules

Clinical Prediction Rules

Project Leads: Dr Matthew Thompson and Dr Richard Stevens

We are currently investigating whether it is possible to use published data to validate clinical prediction rules. Our early results, in validating coronary risk scores such as the Framingham equations in a population with diabetes, are encouraging. Meanwhile, individual-level data sets remain the gold standard for validating prediction rules, and our international collaboration funded by the HTA on prediction rules in acute childhood infections has progressed to the stage of data sharing between countries, which will allow a definitive analysis of prediction rules in this area.